产品编号:S1911

产品描述:AKAP12 antibody

反应种属:

实验方法:

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2890.00

订购:

说明书:

AKAP12 antibody

Cat.#: S1911

Rabbit Polyclonal Antibody

Description

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

Recommended Applications

ICC,IHC,WB

Applications and Recommended Dilution Factors

WB: 1:500-1:3000
IHC: 1:100-1:250,IF:1:100-1:200
ICC: 1:100-1:200

Species Reactivity

Human

Products Data

Sample (30ug whole cell lysate)
A:HeLa S3
5% SDS PAGE
diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded serous OVCA, using AKAP12 antibody at 1:100 dilution.

  

Specificity

Synthetic peptide contain a sequence corresponding to a region within amino acids 1719 and 1782 of AKAP12

Storage Buffer & Conditions

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names

AKAP12, AKAP250, DKFZp686M0430, DKFZp686O0331, FLJ20945, FLJ97621