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Recombinant Human IL-13 Rα1

产品编号:I-548-1

产品描述:Recombinant Human IL-13 Rα1

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Human Interleukin 13 Receptor Alpha 1 (IL-13 Rα1)
Purified No Carrier Protein
(IL13RA1, CD213A1, IL-13Ra, NR4)
Prod. No.: I-548
Source NSO Cells
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C

Description
Background:

Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1) is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13Ralpha1is essential for allergen-induced airway hyperreactivity and mucus hypersecretion.1

Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Human IL-13 Rα1 is Mr 64 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110 kDa.
State of Matter
Lyophilized
Purity
>90% by SDS Page and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin

<1.0 EU/µg as determined by the LAL method

References
1. Wynn TA. et al. (2008) Nat. Immunol. 9: 25
Related Products
Recombinant Mouse IL-13 Rα1 (Leinco Prod. No.: I-564)
Anti-Human IL-13 Rα1 (Leinco Prod. No.: I-625)