产品编号:I-563-1
产品描述:Recombinant Mouse IL-11 Rα
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Mouse Interleukin-11 Receptor Alpha (IL-11 Rα)
Purified No Carrier Protein
(IL11RA, MGC2146)
Prod. No.: I-563
Source NSO Cells
Pkg. Size: 1 mg, 200 µg
Storage: -20°C to -70°C
Description
Background:
Interleukin 11 receptor alpha (IL11RA) is a subunit of the interleukin 11 receptor that is expressed in hematopoietic and other organs.1 IL11RA is a functional target in bone metastasis and is considered as a candidate target in human osteosarcoma and provide leads for the development of novel imaging and therapeutic agents for the management of this malignant tumor.2/sup>
Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Mouse IL-11 Rα is Mr 65 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>97% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
sssspcpqaw gppgvqygqp grpvmlccpg vsagtpvswf rdgdsrllqg pdsglghrlv laqvdspdeg tyvcqtldgv sggmvtlklg fpparpevsc qavdyenfsc twspgqvsgl ptryltsyrk ktlpgaesqr espstgpwpc pqdpleasrc vvhgaefwse yrinvtevnp lgastclldv rlqsilrpdp pqglrvesvp gyprrlhasw typaswrrqp hfllkfrlqy rpaqhpawst vepigleevi tdavaglpha vrvsardfld agtwsawspe awgtpstgpl qdeipdwsqg hgqqleavva qedspaparp slqpdprpld hrdpleqdie grmdpkscdk thtcppcpap ellggpsvfl fppkpkdtlm isrtpevtcv vvdvshedpe vkfnwyvdgv evhnaktkpr eeqynstyrv vsvltvlhqd wlngkeykck vsnkalpapi ektiskakgq prepqvytlp psrdeltknq vsltclvkgf ypsdiavewe sngqpennyk ttppvldsdg sfflyskltv dksrwqqgnv fscsvmheal hnhytqksls lspgkhhhhh h
References
1. Begley CG et al. (1997) Blood 90: 2148
2. Renata Pasqualini et al. (2009) Cancer Res. 69: 1995
Related Products
Anti-Mouse IL-11 Rα (Antigen Aff. Pur.) (Leinco Prod. No.: I-656)
Anti-Mouse IL-11 Rα-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: I-777)
