产品编号:T114
产品描述:Anti-Human TSH-β
反应种属:human
实验方法:ELISA
标记:
规格:1.0 mg
供应商:leinco
价格(RMB):2280.00
订购:
说明书:
Anti-Human Thyroid Stimulating Hormone Beta (TSH-β)
Purified No Carrier Protein
(HCG, GPH, GPHA1, CGA, Thyrotropin)
Monoclonal Antibody
Prod. No.: T114
Clone: 155
Isotype: Mouse IgG
Conc.: 1.0 mg/ml
Pkg. Size: 1.0 mg
Storage: -20°C
Description
Specificity:
Mouse Anti-Human Thyroid Stimulating Hormone Beta (TSH-β) (Clone 155) recognizes Human Thyroid Stimulating Hormone Beta . This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Thyroid-stimulating hormone (TSH) is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3
Affinity:
2 X 1010
Host Species
Mouse
Immunogen
Purified Recombinant Human TSH-β (>98%)
Formulation
This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09% sodium azide.
Cross Reactivity
Paired with Leinco Prod. No. T100, Clone No. 154: TSH 100%, BhCG < 1%, ihCG < 1%, LH < 1%, FSH < 1%. Paired with Leinco Prod. No. T103, Clone No. 171: TSH 100%, BhCG < 1%, ihCG ***%, LH < 1%, FSH < 1%. *** inhibition of reaction
Storage and Stability
For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
References
1. (1998) Bowen A
2. McPherson et al. (2000) Placenta 24: 941
3. Wenger, R H et al. (2003) Wildmann's Clinical Interpretation of Laboratory Tests
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
