产品编号:H108
产品描述:Anti-Human Prolactin-Horseradish Peroxidase
反应种属:human
实验方法:ELISA
标记:
规格:1.0 ml
供应商:leinco
价格(RMB):2670.00
订购:
说明书:
Anti-Human Prolactin
Horseradish Peroxidase (HRPO)
Monoclonal Antibody
Prod. No.: H108
Clone: 172
Isotype: Mouse IgG
Conc.: 0.5 mg/ml
Pkg. Size: 1.0 ml
Description
Specificity:
Mouse Anti-Human Prolactin (Clone 172) recognizes Human Prolactin. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Prolactin is a peptide hormone synthesised and secreted by lactotrope cells in the adenohypophysis (anterior pituitary gland). It is also produced in other tissues including the breast and the decidua. Pituitary prolactin secretion is regulated by neuroendocrine neurons in the hypothalamus, most importantly by neurosecretory dopamine neurons of the arcuate nucleus, which inhibit prolactin secretion. Prolactin is a single chain polypeptide of 199 amino acids with a molecular weight of about 24,000 daltons. Its structure is similar to that of growth hormone and placental lactogen. The molecule is folded due to the activity of three disulfide bonds. Significant heterogeneity of the molecule has been described, thus bioassays and immunoassays can give different results due to differing glycosylation, phosphorylation, sulfation, as well as degradation. The non-glycosylated form of prolactin is the dominant form of prolactin that is secreted by the pituitary gland. Increased serum concentrations of prolactin during pregnancy cause enlargement of the mammary glands of the breasts and increases the production of milk. However, the high levels of progesterone during pregnancy act directly on the breasts to stop ejection of milk. It is only when the levels of this hormone fall after childbirth that milk ejection is possible.
Reporter Molecule:
Horseradish Peroxidase (HRPO) is an enzyme purified from horseradish root with a molecular weight of approximately 44 kDa.
Affinity:
1 X 1010
Host Species
Mouse
Immunogen
Purified Recombinant Human Prolactin (>98%)
Formulation
This horseradish peroxidase conjugate is supplied in a specially formulated stabilization diluent.(Leinco Prod. No.: S509)
Cross Reactivity
Paired with Leinco Prod. No. P101, Clone No. 174: Pro 100%, BhCG < 1%, ihCG < 1%, LH <1%, FSH < 1%. Paired with Leinco Prod. No. P102, Clone No. 180: Pro 100%, BhCG < 1%, ihCG < 1%, LH <1%, FSH < 1%.
Storage and Stability
Stable for at least one year when stored at 2°C - 8°C. Do not freeze.
Reported Applications
ELISA Det
ELISA Detection: This conjugate can be used as one of a matched pair of antibodies for a sandwhich ELISA assay.
Related Products
Recombinant Human Prolactin (Leinco Prod. No.: P168)
Anti-Human Prolactin Purified (Leinco Prod. No.: P101)
Anti-Human Prolactin Horseradish Peroxidase (Leinco Prod. No.: H109)
Anti-Human Prolactin Horseradish Peroxidase (Leinco Prod. No.: H180)
Anti-Human Prolactin Purified (Leinco Prod. No.: P100)
Anti-Human Prolactin Purified (Leinco Prod. No.: P102)
Anti-Human Prolactin-Horseradish Peroxidase (Leinco Prod. No.: H118)
Anti-Human Prolactin (Antigen Aff. Pur.) (Leinco Prod. No.: P283)
Anti-Human Prolactin-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: P294)
Human Prolactin MICRO-ELISA Test Kit (Leinco Prod. No.: T111)
Recombinant Mouse Prolactin (Leinco Prod. No.: P300)
Anti-Mouse Prolactin (Antigen Aff. Pur.) (Leinco Prod. No.: P303)
Anti-Mouse Prolactin-Biotin ( Antigen Aff. Pur. ) (Leinco Prod. No.: B628)
Anti-Mouse Prolactin (Leinco Prod. No.: P310)
Recombinant Mouse Prolactin (Leinco Prod. No.: P244)
Recombinant Rat Prolactin (Leinco Prod. No.: P245)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
