产品编号:I-439
产品描述:Anti-Mouse IFNβ
反应种属:mouse
实验方法:N, IP, WB
标记:
规格:500ug
供应商:leinco
价格(RMB):5025.00
订购:
说明书:
Anti-Mouse IFNβ
Purified Low Endotoxin Functional Formulation
(Inteferon Beta)
Monoclonal Antibody
Prod. No.: I-439
Clone: MIB-5E9.1
Isotype: Armenian Hamster IgG
Conc.: 1.0 mg/ml
Pkg. Size: Custom, 50 µg, 500 µg
Description
Specificity:
Armenian Hamster Anti-Mouse IFNβ (Clone MIB-5E9.1) recognizes Mouse IFNβ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-α proteins and a single IFN-ß protein. The second class, type II IFN, consists of a single protein, IFN-γ. IFN-α and IFN-ß signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-ß has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-ß’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.
Host Species
Armenian Hamster
Formulation
This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Storage and Stability
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
N, IP, WB
Country of Origin
USA
Related Products
Armenian Hamster IgG Isotype Control-Low Endotoxin Functional Formulation (Leinco Prod. No.: I-140)
Anti-Mouse Interferon Beta (IFNβ)-Purified (Leinco Prod. No.: I-440)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
