产品编号:I-433
产品描述:Anti-Mouse IL-1 R1-R-Phycoerythrin
反应种属:mouse
实验方法:FC
标记:
规格:500ug
供应商:leinco
价格(RMB):4125.00
订购:
说明书:
Anti-Mouse IL-1 R1 R-phycoerythrin (R-PE)
(Interleukin-1 R1)
Monoclonal Antibody
Prod. No.: I-433
Clone: JAMA-147
Isotype: Armenian Hamster IgG
Conc.: 0.1 mg/ml
Pkg. Size: 50ug, 500ug
Description
Specificity:
Armenian Hamster Anti-Mouse IL-1 R1 (Clone JAMA-147) recognizes Mouse IL-1 R1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1α and IL-1ß exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1α and IL-1ß, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
Reporter Molecule:
R-phycoerythrin (R-PE) has a molecular weight of 240 kDa and is purified from red algae. R-PE is an intensely bright phycobiliprotein with an absorption maxima at approximately 496, 546 and 565 nm, and a fluorescence emission maximum of ~578 nm.
Host Species
Armenian Hamster
Formulation
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
Reported Applications
FC
Related Products
Armenian Hamster IgG Isotype Control-R-phycoerythrin (Leinco Prod. No.: I-447)
Anti-Mouse IL-1 R1, Type 1-Biotin (Leinco Prod. No.: I-434)
Anti-Mouse IL-1 R1, Type 1-Purified (Leinco Prod. No.: I-432)
Anti-Mouse Interleukin-1 R1 Type 1 Low Endotoxin Functional Formulation (Leinco Prod. No.: I-435)
Products are for research use only. Not for use in diagnostic or therapeutic procedures
