产品编号:I-434

产品描述:Anti-Mouse IL-1 R1 Biotin

反应种属:mouse

实验方法:FC

标记:

规格:500ug

供应商:leinco

价格(RMB):3525.00

订购:

说明书:

Anti-Mouse IL-1 R1 Biotin
(Interleukin-1 R1)
Monoclonal Antibody
Prod. No.: I-434
Clone:     JAMA-147
Isotype:   Armenian Hamster IgG
Conc.:     0.1 mg/ml
Pkg. Size: 50ug, 500ug
Storage:   2-8°C

Description
Specificity:
Armenian Hamster Anti-Mouse IL-1 R1 (Clone JAMA-147) recognizes Mouse IL-1 R1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:
IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1α and IL-1ß exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1α and IL-1ß, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.

Host Species
Armenian Hamster
Formulation
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.

Related Products
Armenian Hamster IgG Isotype Control-Biotin (Leinco Prod. No.: I-445)
Anti-Mouse IL-1 R1, Type 1-R-Phycoerythrin (Leinco Prod. No.: I-433)
Anti-Mouse IL-1 R1, Type 1-Purified (Leinco Prod. No.: I-432)
Anti-Mouse Interleukin-1 R1 Type 1 Low Endotoxin Functional Formulation (Leinco Prod. No.: I-435)

Products are for research use only. Not for use in diagnostic or therapeutic procedures