产品编号:LD-1210

产品描述:Human Cardiac Troponin-I, Grade 1

反应种属:Human

实验方法:

标记:

规格:100 mg

供应商:Life Diagnostics

价格(RMB):3500.00

订购:

说明书:

Human Cardiac Troponin-I
Catalog No. 1210
Analysis SDS PAGE: Major 24 kDa band with
fragmentation bands (integrity > 70%)
Purity 95%
Concentration 0.25 - 2 mg/ml
Buffer 8 M Urea, 50 mM Tris.HCl, 15 mM -
mercaptoethanol, 1 mM EDTA (pH 8.0)
Storage -20oC (avoid repeated freeze thawing)
Source Human cardiac tissue
Troponin I (TnI) is one of three subunits that form the troponin complex of the thin
filaments of striated muscle. The troponin complex serves as a calcium-sensitive switch
that regulates striated muscle contraction. Troponin I binds actin and inhibits actomyosin
ATPase activity in the absence of calcium. Cardiac troponin I is characterized by a
molecular weight of ~24 kDa. It is expressed only in the heart and has proved to be a
specific biomarker for heart disease. Cardiac troponin-I is purified by ion-exchange
chromatography in conjunction with calcium dependent affinity chromatography on
troponin-C agarose.