产品编号:PRO-497-2ug
产品描述:Recombinant Human Ephrin B3(EphrinB3)
反应种属:
实验方法:
标记:
规格:2ug
供应商:Prospec
价格(RMB):2625.00
说明书:
Ephrin B3 Human
Ephrin B3 Human Recombinant
Catalog No. PRO-497
Synonyms:
Ephrin-B3, EPH-related receptor tyrosine kinase ligand 8, LERK-8, EPH-related receptor transmembrane ligand ELK-L3, EFNB3, EPLG8, LERK8, EFL6.
Introduction:
Ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases. The Eph Receptors characteristically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Based upon their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are attached to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Class A ephrins are linked to the membrane by a GPI linkage and bind primarily to EphA receptors; Class B ephrins contain a membrane-spanning region and bind primarily to EphB receptors. Both ephrins and Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos.
EFNB3 is a member of the ephrin gene family.
EFNB3 is significant in brain development as well as in its maintenance.
Furthermore, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a key role in forebrain function.
Description:
Ephrin B3 Human Recombinant (a.a. 135-341) expressed in E.coli, shows a 47 kDa SDS-PAGE.
The Ephrin B3 is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear solution.
Formulation:
Ephrin B3 at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Stability:
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Applications:
• ELISA
• Inhibition Assays
• Western Blotting
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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