产品编号:2478-1
产品描述:AE1 Phospho (pY359) antibody
反应种属:Human
实验方法:WB
标记:
规格:100ul
供应商:Epitomics
价格(RMB):2850.00
订购:
说明书:
Cat.#: 2478-1
The AE1 (anion exchanger, band 3) protein is expressed in erythrocytes and in the A-type intercalated cells of the kidney distal collecting tubule. In both cell types it mediates the electroneutral transport of chloride and bicarbonate ions across the lipid bilayer, and, in erythrocytes (1). AE1 is phosphorylated on Tyr359 and Tyr404 by Lyn in erythrocytes. Phosphorylation of these residues is necessary for correct localization and recycling of kidney AE1 to the basolateral membrane (2).
WB
WB: 1:50,000
Human
A phospho specific peptide corresponding to residues surrounding tyrosine 359 of human AE1 was used as an immunogen.
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
SLC4A1, AE1, DI, EPB3, Band 3 anion transport protein, Solute carrier family 4 member 1
1. Sahr KE, et al. Genomics 24(3):491-501, 1994
2. Toye AM et al. Biochem Soc Symp 72:47-63, 2005
